:root{--navy:#112b3b;--blue:#076b97;--teal:#3e9a9b;--green:#65b98c;--paper:#f5f8f8;--muted:#526b78;--line:#dbe6e8;--radius:18px}*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:96px}body{margin:0;color:var(--navy);font-family:Arial,Helvetica,sans-serif;line-height:1.65;background:#fff}h1,h2,h3,p{margin-top:0}h1,h2,h3{line-height:1.17}h1{font-size:clamp(2.7rem,4.7vw,5rem);font-weight:750;letter-spacing:-.053em;margin:22px 0 28px}h1 em{font-style:normal;color:#63bbab}h2{font-size:clamp(2rem,3.5vw,3.4rem);letter-spacing:-.04em;font-weight:730;margin:12px 0 26px}h3{font-size:1.3rem;letter-spacing:-.02em}p{font-size:1rem;color:var(--muted)}a{color:inherit;text-decoration:none}button{font:inherit;cursor:pointer}.wrap{width:min(1180px,calc(100% - 56px));margin:auto}.skip{position:absolute;top:-70px;background:#fff;padding:8px;z-index:10}.skip:focus{top:4px}.topline{background:#092d42;color:#e3f2f6;font-size:.78rem}.topline-inner{display:flex;justify-content:space-between;gap:10px;padding:6px 0}.top-sep{margin:0 12px}#header{position:sticky;top:0;z-index:8;background:#fff;box-shadow:0 1px 0 var(--line)}.header-inner{height:84px;display:flex;align-items:center;gap:20px}.brand{display:flex;align-items:center;gap:14px;margin-right:auto;min-width:0}.brand img{height:57px;width:auto}.brand-caption{font-size:.68rem;line-height:1.35;font-weight:700;color:#506978;white-space:nowrap}.header-inner nav{display:flex;align-items:center;gap:23px}.header-inner nav a{font-size:.88rem;font-weight:650}.header-inner nav a:hover,.card-link:hover{color:var(--blue)}.languages{display:flex;gap:2px;background:#edf5f6;padding:3px;border-radius:8px}.languages button{background:none;border:0;padding:6px;font-size:.7rem;font-weight:700;border-radius:5px}.languages .active{background:#fff;box-shadow:0 1px 3px #b3c7ce}.menu-button{display:none}.hero{overflow:hidden;background:linear-gradient(123deg,#0d496c,#076993 60%,#137c8e);color:#fff}.hero-grid{display:grid;grid-template-columns:1.3fr .7fr;min-height:620px;align-items:center;gap:70px;padding:72px 0}.eyebrow{font-size:.76rem;font-weight:800;letter-spacing:.17em;color:#167fa0;text-transform:uppercase}.eyebrow.pale,.hero .eyebrow{color:#9bdddc}.hero-lead{font-size:1.16rem;color:#dfedf2;line-height:1.75;max-width:690px}.actions,.contact-actions{display:flex;gap:12px;flex-wrap:wrap;margin-top:35px}.btn{display:inline-flex;justify-content:center;align-items:center;gap:10px;padding:13px 22px;border-radius:8px;font-size:.93rem;font-weight:750;border:1px solid transparent;transition:transform .2s,background .2s}.btn:hover{transform:translateY(-2px)}.btn.primary{background:#6cbf9c;color:#0c3b43}.btn.ghost{border-color:#9ac7d7;color:#fff}.btn.dark{color:#0a526e;border-color:#9ac7d7}.btn.white{background:#fff;color:#095b78}.btn.outline-white{border-color:#a4d3dd;color:white}.hero-points{display:flex;gap:20px;flex-wrap:wrap;margin-top:48px;color:#cfecf1;font-size:.84rem}.hero-points span:before{content:'✓';color:#9befbc;margin-right:7px}.hero-art{position:relative}.hero-art-panel{min-height:320px;background:#f5faf9;border-radius:28px;padding:34px;box-shadow:0 28px 55px #05283b55;display:flex;flex-direction:column;justify-content:center;align-items:center;transform:rotate(2deg)}.hero-art-panel img{width:90%;max-width:310px}.panel-rule{width:66px;height:3px;background:#70c39a;margin:26px 0 20px}.hero-art-panel p{color:#164a5d;text-align:center;font-size:1rem;font-weight:700;line-height:1.5}.hero-art-panel small{font-size:.7rem;color:#6d8997;letter-spacing:.17em}.hero-caption{font-size:.78rem;color:#cae4eb;text-align:center;margin-top:18px}.section{padding:100px 0}.intro{padding:95px 0}.intro-grid{display:grid;grid-template-columns:1fr 1fr;gap:110px}.lead{font-size:1.17rem;line-height:1.8;color:#284b59}.section-header{display:flex;justify-content:space-between;gap:80px;align-items:end;margin-bottom:42px}.section-header h2{max-width:700px;margin-bottom:0}.section-header>p{max-width:320px;margin-bottom:3px}.treatments-section{background:var(--paper)}.cards{display:grid;grid-template-columns:repeat(3,1fr);gap:20px}.treatment-card{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:34px;min-height:390px;display:flex;flex-direction:column;box-shadow:0 6px 22px #123f5108}.card-icon{font-size:.78rem;font-weight:800;color:#6f9aa9;display:flex;justify-content:space-between;margin-bottom:50px}.symbol{font-size:2.2rem;color:var(--teal);font-weight:400}.card-tag{font-size:.73rem;letter-spacing:.11em;font-weight:800;color:var(--blue);margin-bottom:12px}.treatment-card h3{font-size:1.65rem}.treatment-card p{flex:1}.card-link{border:0;background:transparent;padding:0;text-align:left;color:#006f94;font-weight:750;align-self:start}.detail-section{background:#eaf6f5;scroll-margin-top:100px}.detail-section[hidden]{display:none}.detail-wrap{max-width:1000px}.close-detail{background:none;border:0;color:#006888;font-weight:700;margin-bottom:25px;padding:0}.detail-columns{display:grid;grid-template-columns:1.5fr 1fr;gap:50px;margin-top:35px}.detail-aside{background:#fff;border-radius:14px;padding:30px;align-self:start}.detail-aside a:not(.btn){color:#067698;display:block;text-decoration:underline;margin:14px 0}.detail-aside .btn{margin-top:10px}.small{font-size:.79rem}.technology-section{background:#073951;color:#fff}.technology-grid{display:grid;grid-template-columns:1.2fr .8fr;gap:90px}.technology-section h2{max-width:740px}.technology-section p{color:#c7dfe8}.tech-facts{margin-top:36px}.tech-facts>div{padding:14px 0;border-top:1px solid #ffffff29;display:flex;gap:20px;align-items:start}.tech-facts strong{color:#80d3ae}.tech-facts span{color:#e0ebef}.tech-aside{align-self:center;padding:45px;border:1px solid #ffffff36;border-radius:22px;background:#ffffff0a}.tech-circle{border-radius:50%;height:190px;width:190px;margin:0 auto 35px;display:flex;align-items:center;justify-content:center;border:9px solid #4ca9bb;font-size:2.35rem;letter-spacing:-.06em;font-weight:800}.tech-circle span{color:#77d8a4}.tech-aside h3{font-size:1.5rem}.team-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:20px}.team-grid article{padding:26px 18px;border-top:3px solid #71bda4;background:#f5f9f9}.avatar{height:105px;width:105px;display:grid;place-items:center;border-radius:50%;background:linear-gradient(140deg,#d4eef0,#c1e4d1);color:#225d71;font-size:2rem;font-weight:750;margin-bottom:30px}.team-grid h3{font-size:1.12rem}.team-grid p{font-size:.88rem}.collab{margin-top:35px;border:1px solid var(--line);padding:22px 26px;border-radius:10px}.collab strong{font-size:.9rem}.collab p{margin:5px 0 0}.research-section{background:var(--paper)}.research-grid{display:grid;grid-template-columns:.85fr 1.15fr;gap:100px}.publications article{padding:20px 0;border-bottom:1px solid #c9dcdf}.publications article:first-child{padding-top:0}.publications article span{font-size:.75rem;font-weight:800;letter-spacing:.07em;color:#087b9a}.publications h3{font-size:1.15rem;line-height:1.45;margin:7px 0}.publications p{font-size:.85rem;margin:0}.contact-section{background:linear-gradient(135deg,#08618c,#073c57);color:white}.contact-section h2{max-width:580px}.contact-section p{color:#e1f0f2}.contact-grid{display:grid;grid-template-columns:1fr .85fr;gap:95px}.privacy-note{font-size:.8rem;margin-top:35px;max-width:550px}.address-card{background:#fff;color:#163d4e;padding:42px;border-radius:18px}.address-card h3{font-size:1.6rem}.address-card address{font-style:normal;line-height:1.85;color:#426370;margin:18px 0 26px}.address-line{padding:16px 0;border-top:1px solid var(--line);display:grid;gap:3px}.address-line strong{font-size:.81rem}.address-line span{color:#577483;font-size:.9rem}.address-card>a{color:#087c9b;font-weight:750;text-decoration:underline;display:inline-block;margin-top:18px}footer{padding:35px 0;background:#f8fbfb}.footer-grid{display:flex;align-items:end;justify-content:space-between;gap:50px}.footer-grid img{width:105px}.footer-grid p{font-size:.78rem;margin:6px 0}.footer-grid>div:last-child{text-align:right;max-width:490px}.footer-grid small{font-size:.7rem;color:#7a929d}@media(max-width:1000px){.brand-caption{display:none}.header-inner nav{gap:14px}.hero-grid{gap:35px}.technology-grid,.research-grid,.contact-grid{gap:40px}}@media(max-width:750px){.wrap{width:min(100% - 36px,1180px)}.topline-inner>span:first-child{display:none}.header-inner{height:68px;flex-wrap:wrap}.brand img{height:45px}.menu-button{display:block;background:#edf6f6;border:0;border-radius:7px;padding:7px 10px;margin-left:auto}.header-inner nav{display:none;position:absolute;top:68px;left:0;right:0;background:#fff;padding:15px 24px;box-shadow:0 8px 20px #0002;flex-direction:column;align-items:start;gap:14px}.header-inner nav.open{display:flex}.languages{margin-left:0}.hero-grid,.intro-grid,.technology-grid,.research-grid,.contact-grid,.detail-columns{grid-template-columns:1fr;gap:30px}.hero-grid{padding:65px 0 50px}.hero-art{display:none}.hero-points{margin-top:30px}.section{padding:70px 0}.section-header{display:block}.section-header>p{max-width:none;margin-top:18px}.cards,.team-grid{grid-template-columns:1fr}.treatment-card{min-height:0;padding:28px}.card-icon{margin-bottom:23px}.team-grid{grid-template-columns:repeat(2,1fr)}.contact-grid{gap:35px}.footer-grid{display:block}.footer-grid>div:last-child{text-align:left}.tech-aside{padding:28px}}@media(max-width:450px){.topline{font-size:.7rem}.top-sep{margin:0 5px}.brand img{height:38px}.languages button{padding:5px 4px}.team-grid{grid-template-columns:1fr}.avatar{height:75px;width:75px}.address-card{padding:25px}h1{font-size:2.5rem}.actions .btn{width:100%}}

/* Version 2: patient pathway and accessible FAQ */
.journey-section{background:#f9fcfb}.journey-lead{max-width:790px}.journey-steps{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:14px;margin-top:40px}.journey-steps article{padding:25px 23px 22px;border-top:3px solid #4cae9e;background:white;box-shadow:0 10px 35px #0b43600b;border-radius:0 0 12px 12px}.journey-steps article>span{font-size:.78rem;color:#07829a;font-weight:800;letter-spacing:.15em}.journey-steps h3{margin:24px 0 12px;font-size:1.13rem}.journey-steps p{font-size:.91rem;margin:0}.faq-section{background:#eef6f5}.faq-grid{display:grid;grid-template-columns:.8fr 1.2fr;gap:90px}.faq-items details{border-bottom:1px solid #cadcdd;padding:17px 0}.faq-items details:first-child{border-top:1px solid #cadcdd}.faq-items summary{font-weight:730;cursor:pointer;list-style:none;display:flex;justify-content:space-between;gap:20px}.faq-items summary::-webkit-details-marker{display:none}.faq-items summary:after{content:'+';font-size:1.4rem;color:#006b87;line-height:1}.faq-items details[open] summary:after{content:'−'}.faq-items details p{padding-top:14px;max-width:660px}.faq-section .btn{margin-top:20px}a:focus-visible,button:focus-visible,summary:focus-visible{outline:3px solid #d18a1f;outline-offset:4px}@media(max-width:1000px){.header-inner nav{gap:11px}.header-inner nav a{font-size:.8rem}.journey-steps{grid-template-columns:repeat(2,minmax(0,1fr))}.faq-grid{gap:40px}}@media(max-width:750px){.journey-steps,.faq-grid{grid-template-columns:1fr}.journey-steps{gap:12px}}

/* Team portraits: v3 */
.team-portrait{display:block;width:100%;height:230px;object-fit:cover;object-position:center 30%;border-radius:12px;margin:0 0 22px;background:#eaf2f2;}
.team-grid article{overflow:hidden;}
@media(max-width:750px){.team-portrait{height:250px;}}

/* Team portraits: v4 */
.portrait-mg{object-position:center 30%;}
.portrait-am{object-position:center 28%;}
.portrait-fr{object-position:center 30%;}
.portrait-dm{object-position:center 18%;}

/* Version 5 editorial sections */
.about-section{background:#fff}.about-grid{display:grid;grid-template-columns:.95fr 1.05fr;gap:92px}.about-detail{border-left:3px solid #82c6ab;padding-left:36px}.about-detail h3{margin:0 0 7px}.about-detail p{margin:0 0 25px}.international-section{background:linear-gradient(135deg,#0a5578,#073c57);color:#fff}.international-grid{display:grid;grid-template-columns:.95fr 1.05fr;gap:75px;align-items:start}.international-section p{color:#deebee}.international-section .btn{margin-top:22px}.intl-panel{padding:35px;background:#ffffff12;border:1px solid #ffffff44;border-radius:18px}.intl-panel ol{padding-left:22px}.intl-panel li{padding:9px 0;line-height:1.6}.intl-panel li::marker{color:#95e0bc;font-weight:bold}.intl-note{font-size:.81rem;margin:18px 0 0}.research-topics{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:18px}.research-topics article{padding:28px;border-radius:14px;background:#fff;border:1px solid #d8e6e7}.research-topics h3{font-size:1.16rem;margin:11px 0}.research-topics p{font-size:.88rem;margin:0}.research-topics .pub-note{margin-top:10px}.downloads-panel{margin-top:30px;display:grid;grid-template-columns:1fr 1fr;gap:35px;padding:34px;background:#e6f1f1;border-radius:16px}.document-links{display:grid;gap:8px}.document-links a{display:block;background:#fff;border-radius:8px;color:#06698b;font-weight:700;padding:10px 15px;text-decoration:none}.document-links a:hover{text-decoration:underline}@media(max-width:800px){.about-grid,.international-grid,.downloads-panel{grid-template-columns:1fr;gap:30px}.research-topics{grid-template-columns:1fr}.about-detail{padding-left:20px}}

/* v9 — accessible institutional links */
.collab-links{display:flex;flex-wrap:wrap;column-gap:15px;row-gap:7px;margin-top:12px;align-items:center}
.collab-links a{color:#056d92;text-decoration:underline;text-underline-offset:3px;text-decoration-thickness:1px;font-weight:600}
.collab-links a:hover{color:#024c68}
.collab-links span{color:#526b78}
@media(max-width:600px){.collab-links{display:flex;flex-direction:column;align-items:flex-start}}

/* v10: accessible team member profile links */
.linkedin-link{display:inline-flex;gap:8px;align-items:center;font-size:.82rem;font-weight:650;color:#09668b;margin-top:4px;padding:6px 0;text-underline-offset:3px;}
.linkedin-link svg{width:19px;height:19px;flex-shrink:0;}
.linkedin-link:hover{color:#003f59;text-decoration:underline;}
.linkedin-link:focus-visible{outline:3px solid #dc981b;outline-offset:3px;}

/* SIFUS v11 – direct access to reviewed articles */
.publication-article-link{display:inline-flex;align-items:center;gap:5px;width:fit-content;color:#066f92;font-weight:750;font-size:.86rem;line-height:1.5;text-decoration:underline;text-decoration-thickness:1px;text-underline-offset:4px;margin-top:13px;}
.publication-article-link:hover{color:#054561;text-decoration-thickness:2px;}
.publication-article-link:focus-visible,.additional-publications summary:focus-visible{outline:3px solid #d18a1f;outline-offset:4px;}
.research-topics article{display:flex;flex-direction:column;align-items:flex-start;}
.research-topics article .publication-article-link{margin-top:auto;padding-top:13px;}
.additional-publications{margin:32px 0 30px;background:#fff;border:1px solid var(--line);border-radius:14px;padding:0 27px;}
.additional-publications summary{font-size:1.06rem;font-weight:750;color:#08638b;cursor:pointer;padding:25px 0;list-style:none;display:flex;gap:14px;justify-content:space-between;align-items:center;}
.additional-publications summary::after{content:'+';font-weight:500;font-size:1.5rem;}
.additional-publications[open] summary::after{content:'–';}
.additional-publications summary::-webkit-details-marker{display:none;}
.additional-pub-grid{border-top:1px solid var(--line);display:grid;grid-template-columns:repeat(2,minmax(0,1fr));column-gap:36px;}
.additional-pub-grid article{padding:21px 0;border-bottom:1px solid var(--line);min-width:0;}
.additional-pub-grid .additional-citation{font-size:.73rem;font-weight:750;letter-spacing:.04em;color:#167c97;}
.additional-pub-grid h4{font-size:1.04rem;line-height:1.4;margin:7px 0 7px;}
.additional-pub-grid p{font-size:.83rem;margin:0;}
@media(max-width:750px){.additional-pub-grid{grid-template-columns:1fr}.additional-publications{padding:0 20px}}

/* Version 12 — accessible e-mail reveal control, consistent with text links */
.topline .email-reveal-top{border:0;background:transparent;color:inherit;padding:0;margin:0;font-size:inherit;cursor:pointer;line-height:inherit}
.topline .email-reveal-top:hover,.topline .revealed-email:hover{text-decoration:underline}
.topline .revealed-email{color:inherit}
.email-reveal-top:focus-visible,[data-email-reveal]:focus-visible{outline:3px solid #d18a1f;outline-offset:3px}